ABSTRACT
East Java Province has the fourth-highest number of COVID-19 cases among all other provinces Indonesia. This study aimed to examine the spatial effect on confirmed cases of COVID-19 and the risk factors. Data were analyzed using Geoda software to obtain Global Moran's Index and Local Spatial Autocorrelation (LISA) and QGIS 2.8.1 software to make a map. Moran's I scatter plots also used to exploring the bivariate association between COVID-19 cases and potential predictors. The Global Moran's I statistics value shows spatial clustering in COVID-19 cases across the municipalities of East Java Province (Moran's I=0.3986). A positive spatial autocorrelation was observed between COVID-19 cases and population density (Moran's I = 0.2059), vaccination coverage (Moran's I = 0.322), the number of laboratories (Moran's I = 0.2322), ratio of health worker (Moran's I = 0.1617), and household (Moran's I = 0.0866). In comparison, a negative spatial correlation was observed between COVID-19 cases and The Enforcement of Restrictions on Community Activities' levels (Moran's I =-0,2420), average number of family member (Moran's I = 0.0115). The LISA cluster map shows that there were 3 hot spots (Surabaya, Gresik, and Sidoarjo) and 3 cold spots (Sampang, Pamekasan, and Sumenep). Copyright © 2023, Institute of Medico-legal Publication. All rights reserved.
ABSTRACT
Recently, the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been critically recognized and spread rapidly on this planet. Considerable recognition of SARS-CoV-2 has been known with a range of viruses that are more capable to cause diseases in avian and mammals including humans. The virus was found as a main culprit for major defects in respiratory system and thereby caused severe acute respiratory syndrome disease. This has led to depict the mortality in human population. Nevertheless, compromised reports on SARS-CoV-2 has also shown neurological complications in both central nervous system (CNS) and peripheral nervous system (PNS). This virus has notified with neurological defects as stroke, encephalopathy, cerebral edema, erythema, seizures, meningitis, ischemic, agcusia, loss of smell, myalgia and Guillain Barre Syndrome. In this review, we focused on COVID-19 mediated neurodegerieration and its mechanistic episodes on affected patients. We also discuss the possible available therapeutic interventions with clinically investigated drugs against COVID-19 mediated neurological impairment in patients and experimental in vitro and in vivo research models required for the development of drugs and/or vaccines against COVID-19 mediated neurological complications.
ABSTRACT
BACKGROUND: Family physicians have played a unique clinical role during the COVID-19 pandemic. We hypothesized that the pandemic would be associated with significant deleterious effects on clinical activity, educational training, personal safety and well-being. OBJECTIVE: We conducted a national survey to obtain preliminary data that would assist in future targeted data collection and subsequent evaluation of the impact of the pandemic on family medicine residents and teaching faculty. METHODS: An anonymous online survey of residents and faculty was distributed via the Association of Family Medicine Residency Directors list serve between 5/21/2020 and 6/18/2020. Survey questions focused on clinical and educational activities, safety and well-being. RESULTS: One hundred and fifty-three residents and 151 teaching faculty participated in the survey. Decreased clinical activity was noted by 81.5% of residents and 80.9% of faculty and the majority began conducting telehealth visits (97.9% of residents, 91.0% of faculty). Distance learning platforms were used by all residents (100%) and 39.6% noted an overall positive impact on their education. Higher levels of burnout did not significantly correlate with reassignment of clinical duties (residents P = 0.164; faculty P = 0.064). Residents who showed significantly higher burnout scores (P = 0.035) and a decline in levels of well-being (P = 0.031) were more likely to participate in institutional well-being support activities. CONCLUSIONS: Our preliminary data indicate that family medicine residents and teaching faculty were profoundly affected by the COVID-19 pandemic. Future studies can be directed by current findings with focus on mitigation factors in addressing globally disruptive events such as COVID-19.
Family physicians have played a unique clinical role during the COVID-19 pandemic. We hypothesized that the pandemic would be associated with significant deleterious effects on clinical activity, educational training, personal safety and well-being. Towards setting a foundation for further studies, we conducted a national survey to obtain preliminary data that would assist in future targeted data collection and subsequent evaluation of the impact of the pandemic on family medicine residents and teaching faculty. Our preliminary data indicate that family medicine residents and teaching faculty were profoundly affected by the COVID-19 pandemic in all domains studied. Future studies can be directed by current findings with focus on mitigation factors in addressing globally disruptive events such as COVID-19.